2-METHYL-AP-237 is an opioid analgesic drug that was widely used in China to treat pain in cancer patients as of 1986.It is one of the most potent compound among a series of analgesic.




This is not a fun chemical to insufflate. I dosed 10mg intranasally and immediately began to retch. My very first thought as soon as I completed the act was "this tastes/smells like gasoline." Honestly, immediately after consuming it this way, I was instantaneously met with the thought or flavor of gasoline. However, the taste does not linger long. There is moderate discomfort when consuming 2-methyl-AP-237 intranasally -- the sting doesn't last too long eithe though.

5 minutes after insufflating 10mg, I began to notice subtle effects. Kind of a "glossy" feeling in the eyes. Slight muscle relaxation in the back of the neck and shoulders. Not overwhelming at this dosage, but I feel as if there is something going on.

I'll continue to report back as I conduct more experiments.



This stuff is definitely potent.

After that 10mg intranasal dose, I decided to ingest ~23mg orally in a gel capsule.

Its been about an hour and a half since I've ingested the ~23 mg capsule and its hitting me hard. Keep in mind, I have absolutely no tolerance whatsoever.

My body is relaxed, my thoughts are slowed significantly. My attention to detail and awareness of things around me is definitely hindered. Oddly enough, there is a deafening effect going on at the moment... Everything sounds hollow and quiet. Slightly worrisome. Is this a normal side effect from opioid use?



It has now been 6 hours since I ingested the capsule and I am almost back to baseline. The deafening effect I mentioned in my second edit dissipated slowly over the course of 2 hours or so. Odd. I also felt dizzy while I was peaking (about 2.5 hrs after ingesting ~23mg capsule), and pretty light-headed. All the while, I felt very calm and content. Additionally, I worked out a bit harder today than most other days -- yet it still feels like it's been a very relaxing day today. This is a very interesting compound.



It has been two days since the experience above. Today I ingested a capsule containing 25mg of the 2-methyl-AP-237, and it is definitely active at this dosage. It kicks in very hard all at once and quickly diminishes into a mellow sedation that lasts easily 4-5 hours. This is with no tolerance to chemicals of this class. 


This Product is shipped from China with tracking.

Write a review

Please login or register to review


  • Product Code: 2-Methyl-AP-237
  • Availability: In Stock
  • $140.00

  • 2 or more $130.00
  • 5 or more $120.00
  • 10 or more $58.00
  • 25 or more $38.00
  • 50 or more $25.00
  • 100 or more $21.00
  • 250 or more $14.00
  • 500 or more $11.00
  • 1000 or more $8.50

This product has a minimum quantity of 5

Tags: O-DSMT, powder, opioids, opioid, opium