Benzodiazepines

Benzodiazepines

Benzodiazepines (BZD, BZs), sometimes called "benzos", are a class of psychoactive drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring. The first such drug, chlordiazepoxide (Librium), was discovered accidentally by Leo Sternbach in 1955, and made available in 1960 by Hoffmann–La Roche, which, since 1963, has also marketed the benzodiazepine diazepam (Valium). In 1977 benzodiazepines were globally the most prescribed medications.[They are in the family of drugs commonly known as minor tranquilizers.

Benzodiazepines enhance the effect of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABAA receptor, resulting in sedative, hypnotic (sleep-inducing), anxiolytic (anti-anxiety), anticonvulsant, and muscle relaxant properties. High doses of many shorter-acting benzodiazepines may also cause anterograde amnesia and dissociation. These properties make benzodiazepines useful in treating anxiety, insomnia, agitation, seizures, muscle spasms, alcohol withdrawal and as a premedication for medical or dental procedures. Benzodiazepines are categorized as either short-, intermediate-, or long-acting. Short- and intermediate-acting benzodiazepines are preferred for the treatment of insomnia; longer-acting benzodiazepines are recommended for the treatment of anxiety.



Nifoxipam [OUT OF STOCK]

Nifoxipam [OUT OF STOCK]

Nifoxipam is a novel depressant substance of the benzodiazepine class. Now ..

$80.00

Nitrazolam

Nitrazolam

Nitrazolam is a benzodiazepine that has been sold online as a designer drug.It is closely related to..

$140.00

Nitromethaqualone (Methaqualone {Quaaludes} analogue)

Nitromethaqualone (Methaqualone {Quaaludes} analogue)

Nitromethaqualone is an analogue of methaqualone that has similar sedative and hypnotic properties. ..

$170.00

Norflurazepam [OUT OF STOCK]

Norflurazepam [OUT OF STOCK]

Great Benzo!!Desalkylflurazepam is an analytical reference material that is structurally categorized..

$150.00

Pagoclone [OUT OF STOCK]

Pagoclone [OUT OF STOCK]

Pagoclone is a pharmaceutical substance that was under development for stuttering until the 2010s an..

$150.00

Pyrazolam [OUT OF STOCK]

Pyrazolam [OUT OF STOCK]

Pyrazolam (SH-I-04) is a benzodiazepine derivative originally developed by a team led by Leo Sternba..

$150.00

Rilmazafone

Rilmazafone

TGC-RC lab happy to provide our new benzo. Rilmazafone (リスミー, Rhythmy, previously known as 450191-S)..

$200.00

Ro5-4864 [OUT OF STOCK]

Ro5-4864 [OUT OF STOCK]

Ro5-4864 (4'-chlorodiazepam) is a drug which is a benzodiazepine derivative of diazepam. However unl..

$180.00

SL-164 [Analogue of Methaqualone]

SL-164 [Analogue of Methaqualone]

SL-164 is an analogue of methaqualone developed in the late 1960s by a team at Sumitomo. SL-164 has ..

$130.00

XANAX (BLEND) [OUT OF STOCK]

XANAX (BLEND) [OUT OF STOCK]

XANAX is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders. It is ..

$160.00

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